The production methods of Pfizer and Moderna’s COVID-19 vaccines have been thrown into the spotlight due to the discovery of DNA contaminants in the vaccine vials by genomic scientist Kevin McKernan. The DNA found was not only considerable in quantity but also protected by the lipid nanoparticles used for mRNA delivery, implying potential delivery into human cells.
Additionally, a promoter from the SV40 virus, undisclosed in initial vaccine data, was found within the DNA. The presence of this promoter has raised serious questions about the oversight and regulatory processes in vaccine manufacturing. Despite the speed and economic advantages associated with mRNA vaccine technology, concerns around DNA contamination underline the importance of rigorous safety checks.