The pharmaceutical industry is depleting horseshoe crab populations along the Atlantic coast in order to harvest the animals’ blood to make a product used to test injectable medications like vaccines for safety.
The pharmaceutical industry is depleting horseshoe crab populations along the U.S. Atlantic coast with limited accountability — and serious environmental consequences, NPR reported this week.
Drugmakers use a product derived from horseshoe crab blood to test vaccines, injectable medicines and medical devices before injecting them into humans. The product tests for the presence of endotoxins, a toxin found in some bacteria that can cause inflammation, fever, sepsis or death.
The horseshoe crabs’ bright blue blood contains a substance called limulus amebocyte lysate (LAL) that detects the harmful bacterial toxins and captures them in blood clots. No other natural substance is known to work as well to detect the toxins.